NewYork-Presbyterian Hospital Sites: All Centers Medication Use Manual: Guideline Page 2 of 8 _____ E. Modification of a surgical prophylaxis regimen may be necessary in patients DESCRIPTION. Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent compound lincomycin. Prophylactic antibiotic administration should be initiated within one hour before the surgical incision, or within two hours if the patient is receiving vancomycin or fluoroquinolones. Clindamycin in 5% Dextrose Injection in the GALAXY plastic container for intravenous use is composed of clindamycin phosphate equivalent to 300, 600 and 900 mg of clindamycin premixed with 5% dextrose as a sterile solution. Clindamycin is a prescription antibiotic. It is used to treat a wide variety of bacterial infections in the lungs, skin, blood and internal organs. Cleocin Pediatric® clindamycin palmitate hydrochloride for oral solution, USP The chemical name for clindamycin palmitate hydrochloride is Methyl 7-chloro-6, 7, 8- Components Description Dose Sulfadoxine-pyrimethamine (SP) (Fansidar) This fixed-dose combination has been used for many years, causes few adverse effects, is cheap and effective in a single dose, thus decreasing problems associated with adherence and compliance. The antibiotic prophylactic regimens below are recommended by the American Heart Association (AHA) only for patients with underlying cardiac conditions associated with the highest risk of adverse outcome from infective endocarditis. For further information on infective endocarditis, see Infective Endocarditis, Pediatric Bacterial. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use CLINDAMYCIN IN 0.9% SODIUM CHLORIDE injectionsafely and Clindamycin Capsules official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.